The First Survivors of Alzheimer’s

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Basically, Dr. Bredesen’s first book, “The End of Alzheimer’s,” is a roadmap for those who want to reverse or even prevent cognitive decline.  Not only does his book reveal the many causes of Alzheimer’s, but also how those causes can be addressed.  As a result, ALZ symptoms begin to halt and reverse!  Most important, patients need to start with the proper testing, then follow their customized  program to improve cognition.  Thankfully, Dr. Bredesen has developed a “tailor made” program to do just that – The Bredesen ProtocolTM.

In his second book, “The End of Alzheimer’s Program,” Dr. Bredesen reveals new findings including additional subtypes of Alzheimer’s.  You will also read inspiring stories of patients who have reversed cognitive decline and are now thriving. 

So, what can be found in his third book?  Let’s take a look . . .

The End of Alzheimer's (2021 book)
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“The First Survivors of Alzheimer’s” by Dr. Dale E. Bredesen

Book Excerpt:

Excerpted from THE FIRST SURVIVORS OF ALZHEIMER’S by arrangement with Avery Books, a member of Penguin Group (USA) LLC, A Penguin Random House Company. Copyright © 2021, Dale E. Bredesen

Imagine being told that you have Alzheimer’s disease. Because this is such a common disease, there is a very good chance that this will happen to someone you love or someone I love. Now imagine that, instead of being told there is no hope, you are told that this is readily treatable, and that you can expect to get your normal cognition back; what’s more, your children may be assured that they, their children, and your family’s subsequent generations can avoid Alzheimer’s disease. This reversal of fortune is life-changing, with reverberations through the generations ad infinitum.  This was the goal in translating the research that my colleagues and I performed over thirty years into a therapeutic approach.

Do you remember the first time you heard that an untreatable illness had finally become treatable? Down through history, we humans have conquered one disease after another, often through biochemical research, sometimes through anecdotes from tribal medicine, and other times through sheer dumb luck. Regardless of the method, though, the result with each vanquished disease initially feels miraculous: suddenly the death sentences are lifted from thousands or even millions of people, restoring hope and a future for each. These events represent one of the most rewarding aspects of what it means to be human, and they never cease to inspire me:

Najiv was a teenage boy in the 1940s, living in a village in India, when he developed fever and a headache and lapsed into unconsciousness.  He was taken by bullock cart from his village to the city, where the doctor diagnosed bacterial meningitis. At the time, this was typically a rapidly fatal illness. On this occasion, however, the doctor told Najiv’s parents, “Until last week there would have been nothing I could do to save your son, but a new drug has just arrived from England. It is called penicillin.” Instead of dying, then, Najiv made a full recovery, and this is of more than passing interest to all of us: Najiv’s son is one of the most gifted biomedical researchers I have ever met, and his research may offer the best hope for an effective antiviral treatment not just for the COVID‑19 of the current pandemic but also for any subsequent coronavirus pandemics—a brilliant advance with global lifesaving ramifications.

Whether it is Edward Jenner’s development of the first vaccine—it has been pointed out that Jenner is responsible for saving more lives than any other human in history—or Frederick Banting and Charles Best’s discovery of insulin, thus saving millions with diabetes, or David Ho’s development of triple therapy to treat HIV effectively, each of these pioneers conjured hope from hopelessness, each sent a ripple through the reality we live with day to day, creating endless possibilities that did not hitherto exist, and altering the world’s future irrevocably.

The seven survivors you’ll read about in The First Survivors of Alzheimer’s—in their own words—are pioneers as well. You’ll hear from Kristin—the very first person who adopted our protocol (“Patient Zero”)—who had watched her mother sink into dementia, and then was told by her own physician that she was on her way to suffering the same fate, without hope for treatment. How would each of us feel to receive such news from our physician? You’ll also hear from Deborah, who suffered as her beloved father and grandmother were both lost to Alzheimer’s, and then was horrified as she developed the same symptoms they had manifested, wondering what lay in store for her children. And from Edward, who was told to close his businesses and get his affairs in order. And Marcy, who piled up dozens of parking tickets because she could never remember to feed the parking meters. And Sally, a nurse educator who taught her students that medicine had no effective treatment to offer Alzheimer’s patients, then developed it herself and failed a drug trial.  And Frank, who had plans to write a book chronicling his own descent into dementia. And finally from Julie, who asked an expert neurologist if he could simply help her to avoid further decline and was told, “Good luck with that.” The thoughts, concerns, emotions, and ultimate triumphs these survivors experienced are described with a depth of feeling that only those who lived them could express.  All of these pioneers are still on the trail—they survived “terminal” PET scans, MRI scans, family histories, and the prognostications of their physicians, thanks to their own inquisitiveness and industry to find a new solution, their courage to address the underlying drivers of their cognitive decline, and their determination to stick with a novel protocol.

Thanks to these first survivors, the way is now clear for the millions more in need, for both prevention and reversal of cognitive decline. These pioneers are catalyzing a paradigm shift in the way we think about, evaluate, prevent, and treat Alzheimer’s disease and the pre-Alzheimer’s conditions, MCI (mild cognitive impairment) and SCI (subjective cognitive impairment).

But why did it take so long? Alzheimer’s disease was first described way back in 1906, yet the first survivors did not begin treatment until 2012, over a century later. Why so long? The fundamental difference between the way people were treated from 1906 until 2012 (and, unfortunately, the way most are still treated, unsuccessfully, today) and the therapeutics used for all of the survivors, is an obvious one: with all previous approaches, patients were given a Procrustean prescription for a single drug, such as Aricept, that has nothing to do with what is actually causing the cognitive decline.

In contrast, each of the survivors was evaluated for the various factors that were causing the decline itself, then those contributors were targeted with the personalized, precision medicine protocol we dubbed ReCODE (for “reversal of cognitive decline”). Some had undiagnosed infections—Marcy, for example, as you’ll see from her story, had an undiagnosed infection from a tick bite, a relatively common one called ehrlichiosis, and treating that, along with her multiple other contributors, was important for best outcome; Sally, on the other hand, had exposure to mycotoxins (toxins produced by some molds), and removing her exposure was critical to her success. Each of the survivors you’ll hear from had a different set of contributors, so that the optimal protocol for each survivor was different.

Book Summary:

First person stories of patients who recovered from Alzheimer’s Disease–and how they did it.

It has been said that everyone knows a cancer survivor, but no one has met an Alzheimer’s survivor – until now. In his first two books, Dr. Dale Bredesen outlined the revolutionary treatments that are changing what had previously seemed like the inevitable outcome of cognitive decline and dementia.  And in these moving narratives, you can hear directly from the first survivors of Alzheimer’s themselves–their own amazing stories of hope told in their own words.
These first person accounts honestly detail the fear, struggle, and ultimate victory of each patient’s journey. They vividly describe what it is like to have Alzheimer’s. They also drill down on how each of these patients made the program work for them–the challenges, the workarounds, the encouraging results that are so motivating. Dr. Bredesen includes commentary following each story to help point readers to the tips and tricks that might help them as well.

Dr. Bredesen’s patients have not just survived; they have thrived to rediscover fulfilling lives, rewarding relationships, and meaningful work. This book will give unprecedented hope to patients and their families.

NOTE:  Be sure to watch the corresponding video – Meet The First Survivors of Alzheimer’s.


Final Thoughts:

First thing to remember – Dr. Bredesen’s books are written for everyone and that includes the medical community.  His books are a wealth of information, yet the material is easily understood.  In other words, you don’t need to be a doctor to follow his roadmap to better cognition!

Again, it’s important to realize that results can be seen even if the patient isn’t following their customized  program perfectly.  Dr. Bredesen discovered there are 36 or more causes of Alzheimer’s.  He uses the example of a roof with 36 holes.  Once enough of the holes in your roof are patched (or insults to your brain addressed), the damage (or ALZ symptoms) begin to halt and reverse.

Above all, just know there is a successful treatment for Alzheimer’s and dementia available now.  The Bredesen ProtocolTM has helped hundreds of people halt and reverse their cognitive decline.  It is not a cure.  Those who fall off their program notice a decline in their thought processes.  It is a treatment that must be maintained, but is so worth it!  Hold onto that hope.  Watch and listen to ALZ Survivor Stories.  Check out HOW IS THIS POSSIBLE?  Then go to the GET STARTED page.

Here’s the difference between a standard treatment and a “tailor made” customized  treatment.

Standard Treatment Customized Treatment
one-size-fits-all ALZ treatment doesn't work customized ALZ treatment works
This standard treatment includes:
 – Doctor treating you blindly
 – Pills that may only be helpful for awhile
 – Advice to put your affairs in order
 – No hope
The Bredesen ProtocolTM includes:
 – Testing to reveal your ALZ causes
 – Customized program to target causes
 – Diet & Lifestyle Strategies
 – Hope, knowing others are ALZ survivors!

Therefore, it’s not a silver bullet, but customized  silver buckshot that’s needed to combat dementia and Alzheimer’s. 
In conclusion, Dr. Bredesen’s team at Apollo Health will answer any questions you have.  If you’re ready now to reverse your cognitive decline or help a loved one get started, here is the information you need.

Contact Apollo Health:

   Phone:  800-450-0805

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abbreviation for Alzheimer’s Disease
Alzheimer’s Disease
a type of dementia and a progressive disease of the brain that slowly causes impairment in memory and cognitive function. Alzheimer’s disease happens when the brain tries to protect itself from three metabolic and toxic threats: 1 - Inflammation (from infection, diet or other causes) 2 - Decline and shortage of supportive nutrients, hormones and other brain-supporting molecules 3 - Toxic substances such as metals or biotoxins (poisons produced by microbes such as molds) The protective response causes APP (Amyloid Precursor Protein, the long molecule that protrudes from neurons) to be cut into four fragments, including amyloid-beta, that downsize the neural network and eventually destroy synapses and neurons. When the APP molecule is cut into those four pieces, it is not cut into the two pieces that nourish and maintain synapses. Alzheimer's disease is a state of the brain in which there is an imbalance between the reorganization of synapses that have outlived their usefulness (and which the brain can stand to lose - healthy destruction) and the maintenance or creation of existing and new synapses (which the brain needs to sustain old memories and form new ones, as well as perform other cognitive functions). That imbalance  comes from too many  of the synapse- and neuron-destroying quartet  of molecules snipped from APP and too few  of the synapse- and neuron-sustaining duo  of molecules snipped from APP.
abbreviation for apolipoprotein E, a gene variant (allele) which is a protein that carries lipids – i.e. fats. Carrying one ApoE4 (inherited from one parent) increases your lifetime risk of Alzheimer’s to 30 percent. Carrying two copies (from both parents) increases it to 50 to 90 percent. That compares to a risk of only about 9 percent in those who carry zero copies of this allele.
abbreviation for Amyloid Precursor Protein, the long molecule that protrudes from neurons
metabolic and genetic testing that identifies cognitive decline or what may be putting you at risk for it
umbrella term for a group of symptoms (a syndrome) without a definitive diagnosis. Dementia is a group of symptoms that affect mental cognitive tasks such as memory and reasoning. (Alzheimer’s Disease is the most common type of dementia.)
Early Alzheimer’s Disease
an early onset of Alzheimer’s Disease and uncommon form of dementia that typically affects those under the age of 65
Functional Medicine
a systems biology–based approach that focuses on identifying and addressing the root cause of disease
carrying 1 copy of the ApoE4 genetic variant
carrying 2 copies of the ApoE4 genetic variant
Integrative Medicine
healing-oriented medicine that takes account of the whole person, including all aspects of lifestyle. It emphasizes the therapeutic relationship between practitioner and patient, is informed by evidence, and makes use of all appropriate therapies.
Ketoflex 12/3
anti-Alzheimer’s diet to include at least 12 hours of fasting, with the first 3 hours of that fast starting after dinner. It is largely plant based, but flexible as it does allow for small amounts of meat or fish.
Mild Cognitive Impairment
MCT oil
an abbreviation for medium chain triglyceride (a saturated fat) which is found in coconut oil.  Alzheimer's impairs the brain's ability to use sugar.  An MCT ketogenic diet offers an alternative energy source:  ketones.  This allows brain cells to survive better, blocking a receptor in the brain that causes memory loss.
Subjective Cognitive Impairment – a precursor to MCI (Mild Cognitive Impairment)
The Bredesen ProtocolTM
treatment program developed by Dr. Dale E. Bredesen to prevent and reverse cognitive decline (also known as The ReCODE ProtocolTM)

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