How Is This Possible?

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The Bredesen Protocol

At this time, there is no “cure” for Alzheimer’s, but there is a successful treatment to prevent and reverse cognitive decline. The person to thank for this is Dr. Dale E. Bredesen, a neurologist and neuroscientist, whose 30 years of research have culminated in The Bredesen ProtocolTM. This has also been known as The ReCODE ProtocolTM. ReCODE stands for reversing cognitive decline and this is just what has happened for hundreds of people who remain on their individualized program. There are currently over 2,000 people on the Protocol. Due to the Protocol, one patient has continued functioning normally for 7 years!

Dr. Bredesen’s three decades of research have culminated in the first reversals of cognitive decline in Early Alzheimer’s Disease and its precursors, MCI (mild cognitive impairment) and SCI (subjective cognitive impairment). As Dr. Bredesen would say”…it’s no longer a mystery illness – we know why you get it and we know what to do about it and how to prevent it.”

Visit Apollo Health to learn more about Dr. Bredesen, his research, and the Protocol he developed.

A brief overview of The Bredesen ProtocolTM:

The first video on the Home page gives a brief explanation of The Bredesen ProtocolTM. Lorie Johnson, CBN Health News Reporter, interviews Dr. Bredesen and also showcases a woman on the Protocol. This short 5 minute video begins with Sally who was diagnosed with Early Alzheimer’s. Her husband, Martin, searched the Internet for anything that would help her, and he discovered Dr. Bredesen and his ReCODE Protocol. He found a doctor certified in The Bredesen ProtocolTM and following the program, Sally began to get better and “come back” as he says.  (Keep in mind this is a woman with Alzheimer’s who is using her own thought processes to explain in detail some of what she does on the Protocol.)  Staying on the program, she is functioning normally. This short video speaks volumes.

Sally isn’t the only one to reverse her cognitive decline. There are hundreds of people on the Protocol who have done the same and now have their lives back. These are people who were diagnosed with Alzheimer’s and in some cases told to begin the process of closing down their businesses as the disease would soon render them incapable. However, once they sought the proper treatment from a Bredesen trained physician or health care practitioner, the Protocol was implemented and with strict adherence to their individualized program, their decline halted and their cognition began to improve. These patients were not only able to return to work, but in some cases expand their businesses, travel the world, or learn a new language!

The reason this Protocol works is because the trained physician isn’t treating the patient blindly. Instead, the doctor follows a set protocol step by step to include the following:

  • An evaluation and testing (Dr. Bredesen calls it a CognoscopyTM).
    These simple tests include:

       –  blood tests (chemical, hormonal, metabolic and toxicity tests)
       –  genetic tests
       –  a simple online cognitive assessment
       –  an MRI with an automatic computer assessment of brain volumes

The CognoscopyTM reveals which synapse-destroying processes might be at work in the brain, and which synapse-maintaining processes might not be firing on all cylinders. This leads to synapse loss (causing the loss of memory and cognitive abilities). 

  • From the CognoscopyTM, a computerized program (using an algorithm) develops an assessment and personalized program for the patient.
  • Alzheimer’s Disease happens when the brain tries to protect itself from three metabolic and toxic threats:
       –  Inflammation (from infection, diet or other causes)
       –  Decline and shortage of supportive nutrients, hormones and other brain-supporting molecules
       –  Toxic substances such as metals or biotoxins (poisons produced by microbes such as molds)
    Whatever threats are revealed through testing, they are then addressed.
  • The Protocol also focuses largely on diet, fasting, exercise, sleep, stress reduction, and other lifestyle factors. 

Using a specialized computer program, the physician is able to track the patient’s progress. The patient’s regimen is continually tweaked to optimize success for the patient.

NOTE: To see how important diet, fasting, exercise, sleep, stress reduction and other lifestyle changes are, click here to listen to a podcast  of Julie G. sharing her story and journey to health.

Dr. Bredesen’s book, published in August 2017, is titled The End of Alzheimer’sThe First Program to Prevent and Reverse Cognitive Decline.” Interspersed throughout the book are patient stories including their diagnoses, what testing revealed, and how their individualized Protocols brought them “out of the fog.”

It’s an in-depth look at the many factors which cause Alzheimer’s. The Bredesen ProtocolTM is not a one-size-fits-all  treatment. Surprisingly, there are even different types of Alzheimer’s. That is why each person must be tested to find out what factors have caused their Alzheimer’s.

Order this book here.

His book lists the specific tests needed and how The Bredesen ProtocolTM addresses the causes and deficiencies found through testing. The anti-Alzheimer’s diet – Ketoflex 12/3 is explained and a chart is included to show which foods should be eaten and which ones to avoid. This book is a roadmap for those who want to prevent or reverse cognitive decline.

Dr. Bredesen has discovered there are at least 36 contributing factors to Alzheimer’s.  He relates those 36 factors to 36 holes in a roof. Once you have enough of them patched, then the rest aren’t serious enough to let much water into your house. The same is true with Alzheimer’s. Once enough of the network components have been optimized, the pathogenetic process can be halted or reversed.

Dr. Bredesen has trained over 1,000 physicians, neuropsychologists, nurses, health coaches, and nutritional therapists from 12 different countries and throughout the U.S. He continues to offer training as more physicians, etc. learn about his approach to preventing and reversing Alzheimer’s.

Within The Bredesen ProtocolTM, two separate programs are offered – PreCODE and ReCODE.


The PreCODE Program:

PreCODE is intended for individuals who are asymptomatic and interested in prevention of cognitive decline. It was designed for adults of any age with a family history of dementia, with risk factors such as pre-diabetes or inflammation, and for all of us who are over 45 years of age.

The PreCODE Program starts with a PreCODE Report.  This Report will be generated following lab tests (not included & only available to U.S. residents) and completion of online medical questionnaires and cognitive assessments. You can download a sample report here

Your PreCODE Report will specifically identify any emerging Alzheimer’s subtypes and provide personalized instructions (including supplement recommendations) to prevent cognitive decline and enhance your cognition.


The ReCODE Program:

ReCODE is designed for individuals who require more resources to combat cognitive decline. Bredesen trained practitioners can provide quality, precision care to help you reverse existing symptoms. ReCODE is most effective when used as early as possible in the disease process.

The ReCODE Program starts with a ReCODE Report.  This Report will be generated following lab tests (not included & only available to U.S. residents) and completion of online medical questionnaires and cognitive assessments. Download a sample report here

Your ReCODE report will specifically identify what is driving your current symptoms leading to an identification of your specific Alzheimer’s subtypes and provide personalized instructions including comprehensive supplement recommendations designed to halt progression and reverse symptoms of cognitive decline while optimizing overall health.


More information on The PreCODE Program and The ReCODE Program may be found by visiting Apollo Health.  There, you can also watch a video which explains the science behind The Bredesen ProtocolTM.


Find Bredesen Trained Practitioners

You can search for Bredesen trained physicians and health care practitioners in your area here.


Contact Apollo Health to get started or ask questions.

  Phone:  800-450-0805


Bredesen Training & Certification

Information regarding ReCODE 2.0 Training for health care practitioners can be found here.



Helpful Information
Dr. Bredesen’s research findings and
The Bredesen Protocol

ApoE4 support and discussion:

Contact Apollo Health:

Phone: 800-450-0805

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abbreviation for Alzheimer’s Disease
Alzheimer’s Disease
a type of dementia and a progressive disease of the brain that slowly causes impairment in memory and cognitive function. Alzheimer’s disease happens when the brain tries to protect itself from three metabolic and toxic threats: 1 - Inflammation (from infection, diet or other causes) 2 - Decline and shortage of supportive nutrients, hormones and other brain-supporting molecules 3 - Toxic substances such as metals or biotoxins (poisons produced by microbes such as molds) The protective response causes APP (Amyloid Precursor Protein, the long molecule that protrudes from neurons) to be cut into four fragments, including amyloid-beta, that downsize the neural network and eventually destroy synapses and neurons. When the APP molecule is cut into those four pieces, it is not cut into the two pieces that nourish and maintain synapses. Alzheimer's disease is a state of the brain in which there is an imbalance between the reorganization of synapses that have outlived their usefulness (and which the brain can stand to lose - healthy destruction) and the maintenance or creation of existing and new synapses (which the brain needs to sustain old memories and form new ones, as well as perform other cognitive functions). That imbalance  comes from too many  of the synapse- and neuron-destroying quartet  of molecules snipped from APP and too few  of the synapse- and neuron-sustaining duo  of molecules snipped from APP.
abbreviation for apolipoprotein E, a gene variant (allele) which is a protein that carries lipids – i.e. fats. Carrying one ApoE4 (inherited from one parent) increases your lifetime risk of Alzheimer’s to 30 percent. Carrying two copies (from both parents) increases it to 50 to 90 percent. That compares to a risk of only about 9 percent in those who carry zero copies of this allele.
abbreviation for Amyloid Precursor Protein, the long molecule that protrudes from neurons
metabolic and genetic testing that identifies cognitive decline or what may be putting you at risk for it
umbrella term for a group of symptoms (a syndrome) without a definitive diagnosis. Dementia is a group of symptoms that affect mental cognitive tasks such as memory and reasoning. (Alzheimer’s Disease is the most common type of dementia.)
Early Alzheimer’s Disease
an early onset of Alzheimer’s Disease and uncommon form of dementia that typically affects those under the age of 65
Functional Medicine
a systems biology–based approach that focuses on identifying and addressing the root cause of disease
carrying 1 copy of the ApoE4 genetic variant
carrying 2 copies of the ApoE4 genetic variant
Integrative Medicine
healing-oriented medicine that takes account of the whole person, including all aspects of lifestyle. It emphasizes the therapeutic relationship between practitioner and patient, is informed by evidence, and makes use of all appropriate therapies.
Ketoflex 12/3
anti-Alzheimer’s diet to include at least 12 hours of fasting, with the first 3 hours of that fast starting after dinner. It is largely plant based, but flexible as it does allow for small amounts of meat or fish.
Mild Cognitive Impairment
MCT oil
an abbreviation for medium chain triglyceride (a saturated fat) which is found in coconut oil.  Alzheimer's impairs the brain's ability to use sugar.  An MCT ketogenic diet offers an alternative energy source:  ketones.  This allows brain cells to survive better, blocking a receptor in the brain that causes memory loss.
Subjective Cognitive Impairment – a precursor to MCI (Mild Cognitive Impairment)
The Bredesen ProtocolTM
treatment program developed by Dr. Dale E. Bredesen to prevent and reverse cognitive decline (also known as The ReCODE ProtocolTM)

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