The TRUTH About Alzheimer’s Drugs

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The pharmaceutical company, Biogen, announced in March 2019 that it was halting two large studies of the drug, aducanumab, for treatment of Alzheimer’s Disease. In October 2019, Biogen was back in the news with the hope of getting FDA approval for their drug as additional analyses suggested it might have some effect at higher doses. Biogen claims its anti-amyloid drug, aducanumab, may slow cognitive decline in some patients experiencing the earliest signs of Alzheimer’s Disease.

Biogen, Merck & Co., Eli Lilly & Co., and others have spent great amounts of time and money working on anti-amyloid drugs. Neuroscientists, like Dr. Dale Bredesen, know the production of amyloid is a healthy protective response to insults in the brain. Why then are drug companies continuing down this rabbit hole? If amyloid plaque build up is a result  of the disease, why not target one of the causes  of the disease common to many – such as inflammation.

Today, we expect to visit our doctor, list our symptoms and leave the office knowing the drug(s) prescribed will get us back to normal. With dementia and Alzheimer’s, however, we’re expecting drugs to do the impossible. No pill or two could address the 36 or more known causes of Alzheimer’s. We know the typical ALZ drugs now being prescribed may work for awhile, but soon it seems those drugs may be doing more harm than good for the patient. It’s almost like taking antibiotics for a virus. The doctor knows antibiotics won’t kill viruses and their overuse could lead to antibiotics being ineffective. But, the patient just feels better knowing they have a drug in hand.

Rather than rely on the drug companies, we can take action now using Diet & Lifestyle Strategies to Improve Cognition. To combat a multi-factored foe like dementia/ALZ, effort is needed on our part. Also, we must have someone in our corner to make sure we are daily doing all that’s needed.

The worst thing we can do is to listen to those who say there is no hope and there are no ALZ survivors. That is simply FALSE. There are survivors and there is much we can do to prevent  and reverse  dementia and Alzheimer’s without pharmaceutical drugs. It all depends on us and the effort we put forth.

Our first action can be choosing a treatment to follow. Which treatment do you or your loved one deserve?

Standard Treatment Customized Treatment
one-size-fits-all ALZ treatment doesn't work customized ALZ treatment works
This standard treatment includes:
 – Doctor treating you blindly
 – Pills that may only be helpful for awhile
 – Advice to put your affairs in order
 – No hope		 The Bredesen ProtocolTM includes:
 – Testing to reveal your ALZ causes
 – Customized program to target causes
 – Diet & Lifestyle Strategies
 – Hope, knowing others are ALZsurvivors!

NOTE: It’s not a silver bullet, but customized  silver buckshot that’s needed to combat dementia and Alzheimer’s. If you are unable to make use of The Bredesen ProtocolTM, get started with Alzheimer’s Diet & Lifestyle Strategies to Improve Cognition. Making these changes will have a greater impact than you might imagine. These same strategies can also be used to prevent  ALZ. GET STARTED TODAY!

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The TRUTH About Alzheimer’s Drugs . . .

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Glossary


ALZ

abbreviation for Alzheimer’s Disease

Alzheimer’s Disease

a type of dementia and a progressive disease of the brain that slowly causes impairment in memory and cognitive function. Alzheimer’s disease happens when the brain tries to protect itself from three metabolic and toxic threats:

1 - Inflammation (from infection, diet or other causes)

2 - Decline and shortage of supportive nutrients, hormones and other brain-supporting molecules

3 - Toxic substances such as metals or biotoxins (poisons produced by microbes such as molds)


The protective response causes APP (Amyloid Precursor Protein, the long molecule that protrudes from neurons) to be cut into four fragments, including amyloid-beta, that downsize the neural network and eventually destroy synapses and neurons. When the APP molecule is cut into those four pieces, it is not cut into the two pieces that nourish and maintain synapses.

Alzheimer's disease is a state of the brain in which there is an imbalance between the reorganization of synapses that have outlived their usefulness (and which the brain can stand to lose - healthy destruction) and the maintenance or creation of existing and new synapses (which the brain needs to sustain old memories and form new ones, as well as perform other cognitive functions). That imbalance  comes from too many  of the synapse- and neuron-destroying quartet  of molecules snipped from APP and too few  of the synapse- and neuron-sustaining duo  of molecules snipped from APP.


ApoE4

abbreviation for apolipoprotein E, a gene variant (allele) which is a protein that carries lipids – i.e. fats. Carrying one ApoE4 (inherited from one parent) increases your lifetime risk of Alzheimer’s to 30 percent. Carrying two copies (from both parents) increases it to 50 to 90 percent. That compares to a risk of only about 9 percent in those who carry zero copies of this allele.

APP

abbreviation for Amyloid Precursor Protein, the long molecule that protrudes from neurons


Cognoscopy

metabolic and genetic testing that identifies cognitive decline or what may be putting you at risk for it

Dementia

umbrella term for a group of symptoms (a syndrome) without a definitive diagnosis. Dementia is a group of symptoms that affect mental cognitive tasks such as memory and reasoning. (Alzheimer’s Disease is the most common type of dementia.)

Early Alzheimer’s Disease

an early onset of Alzheimer’s Disease and uncommon form of dementia that typically affects those under the age of 65

Functional Medicine

a systems biology–based approach that focuses on identifying and addressing the root cause of disease

Heterozygous

carrying 1 copy of the ApoE4 genetic variant

Homozygous

carrying 2 copies of the ApoE4 genetic variant

Integrative Medicine

healing-oriented medicine that takes account of the whole person, including all aspects of lifestyle. It emphasizes the therapeutic relationship between practitioner and patient, is informed by evidence, and makes use of all appropriate therapies.

Ketoflex 12/3

anti-Alzheimer’s diet to include at least 12 hours of fasting, with the first 3 hours of that fast starting after dinner. It is largely plant based, but flexible as it does allow for small amounts of meat or fish.

MCI

Mild Cognitive Impairment

MCT oil

an abbreviation for medium chain triglyceride (a saturated fat) which is found in coconut oil.  Alzheimer's impairs the brain's ability to use sugar.  An MCT ketogenic diet offers an alternative energy source:  ketones.  This allows brain cells to survive better, blocking a receptor in the brain that causes memory loss.

SCI

Subjective Cognitive Impairment – a precursor to MCI (Mild Cognitive Impairment)

The Bredesen Protocol

treatment program developed by Dr. Dale E. Bredesen to prevent and reverse cognitive decline (also known as The ReCODE ProtocolTM)

 
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